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In a boost for the development of nanomedicines to study and diagnose inflammatory diseases, City College of New York biomedical engineer Ryan M. Williams is the recipient of a $1.96 million grant from the NIH’s (NIGMS). 

The funding, over five years, is part of the MIRA ESI program (Maximizing Investigator's Research Award for Early Stage Investigators) that supports the nation's most highly talented and promising young investigators. Williams’ award is titled: “Investigating real-time multi-system cytokine signaling in chronic disease.” 

“The main goals of the grant are to engineer implantable novel fluorescent nanosensors to be used as tools to study pro-inflammatory proteins (cytokines) in chronic diseases, such as cardiovascular disease, hypertension, cancer, and neurodegenerative diseases including Alzheimer's and Parkinson’s,” said Williams.

 An assistant professor in the City College’s Grove School of Engineering, Williams will work with his biomedical engineering colleague Steve Nicoll, whose lab is collaborating in the design of the implantable nanosensors.

Research will also take place in whose mission is to design and translate nanomedicines relating to targets in inflammatory diseases. Specifically, it is developing kidney-targeted polymeric nanoparticles as therapeutic tools for renal diseases and implantable optical nanosensor devices as diagnostic and research tools for cancer and other inflammation-driven diseases.

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